Sophora Japonica L.


CAS No.: 7085-55-4

Molecular Formula: C30H36O16

Molecular Weight: 742.67

Specification: EP, DAB1999, Orally Grade


Troxerutin also called Venoruton, Vitamin P4, is classified as biofla­vanoid. It is a derivate of Rutin through hydroxyethylation,able to use directly as API. It can be used for the treatment of varication, thrombosis, and cerebrovascular disease, thrombosis has better water-solubility and drug effect than Rutin.

Troxerutin is useful in inhibiting the aggregation of red blood cells and platelets, Preventing thrombogenesis, increasing blood oxygen content, and promoting neovascularity at the same time.

It can also build up capillary resistance, lower capillary permeability so that to prevent edema caused by increasing capillary permeability. It is with more functions, such as an anti-radiation lesion, anti-inflammatory, anti-allergic, anti-ulcer, etc.



Product NameTroxerutin
Botanical SourceSophora Japonica L
Used PartFlower Bud
AppearanceYellowish-green, crystalline powder, hydroscopic
SolubilityFreely soluble in water, slightly soluble in ethanol(96%) and practically insoluble in methylene chloride
IdentificationA) IR: The infrared spectrum should be conformed to the Troxerutin CRS. B) The principal peak in the chromatogram obtained with the test solution is similar in position and size to the peak in the chromatogram obtained with the reference solution
-Principal peak≥80%
-One peak≤10%
-Other each peak≤5%
Ethylene Oxide(GC)≤1ppm
Loss on Drying≤5.0%
Sulphated Ash≤0.4%
Assay(dried substance)95.0%~105.0%
Residual Solvents 
Total Plate Count≤1000cfu/g
-Yeast & Mold≤100cfu/g
StoragePreserve in tight containers, protected from strong light and high heat.


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